Where to Stay in Prague for a Business Trip: Top Hotels and Tips
Prague Wenceslas Square - Prague 1
Planning a business trip to Prague? Choosing the right accommodation is key to balancing work and relaxation. In this guide, we’ll explore the best neighborhoods and hotels in Prague tailored for business travelers—offering convenient access to meeting venues, transport links, and comfortable amenities to make your stay productive and enjoyable.
New Town - Prague’s Downtown
New Town is an ideal area for travelers visiting Prague on a business trip. Its central location offers easy access to major tourist sites—perfect for a stroll through the medieval town when time allows. You’ll also be just steps away from the Main Train Station and key business districts, making it convenient for both work and leisure.
Here is our Top New Town Hotel Picks:
Jalta Boutique Hotel - This modern hotel on Wenceslas Square offers all the comfort and style you could want for your vacation. As a unique perk, there’s a former nuclear bunker located right beneath it that you can visit. Click here to see availability and prices!
Hermitage Hotel Prague - Standing at the foot of Vyšehrad Hill, this luxurious hotel will be a treat on your Prague stay. Don’t forget to check out their rooftop! Click here to see availability and prices!
Almanac X Alcron Prague - This luxury hotel a few steps away from Wenceslas Square has been accommodating guests since 1932 and recently went through a full-blown renovation. Click here to see availability and prices!
NH Collection Prague Carlo IV - Featured in several movies as a symbol of wealth and comfort, this hotel is located right between Wenceslas Square and the main train station. Click here to see availability and prices!
INNSiDE by Meliá Prague Old Town - This swanky hotel is barely 10 years old, yet it has already established itself as one of the most comfortable places to stay in the city. Despite what the name suggests, it is located right on the New Town’s hub - the Republic Square. Click here to see availability and prices!
Hotel Clement - This hotel is just a short walk from the Old Town and a perfect option for travelers who value comfort and exceptional service. Click here to see availability and prices!
Miss Sophie's Downtown - If you want to get to your room as soon as you leave the Main Train station, this is a perfect spot to stay! Click here to see availability and prices!
Hotel Garden Court - This centrally positioned hotel, offers great value for your money and attentive service. You will be just 12 minutes away from the Old Town, and 700 meters away from the Wenceslas Square. Click here to see availability and prices!
Wenceslas Square Hotel - Czech Leading Hotels - This hotel on Wenceslas Square provides friendly service, bright rooms, and a great terrace view. Click here to see availability and prices!
MOSAIC HOUSE Design Hotel - Hip and fun, this New Town accommodation is just a few minutes away from Charles Square and 1 tram stop away from the city center. Click here to see availability and prices!
Prague Marriott Hotel - This iconic chain is located right next to the Powder Gate at Republic Square, providing easy access to both the Old Town and New Town areas. Click here to see availability and prices!
Hilton Prague Old Town - Don’t be confused by the name—this famous chain is located right near the Old Town, making it a great place to stay. Click here to see availability and prices!
Karlín – Prague’s Silicon Valley
The trendy district of Karlín is often called the “Silicon Valley of Prague” for a reason. It’s one of the most modern areas among Prague’s historic neighborhoods, with many companies choosing it as the location for their headquarters.
Hotel Mucha - Situated in the Karlín district, this modern and stylish hotel will be a great resting base for your work trip. Click here to see availability and prices!
The Hotel Fitzgerald - The Swanky Hotel Fitzerald is located in Karlín district, just 3 metro stops away from the city center. Click here to see availability and prices!
Hotel Royal Prague - This modern and affordable hotel will be a cozy shelter on your business trip. Click here to see availability and prices!
Valery in the Old Town of Prague
💼 Tips for Your Prague Business Trip
1. Be cautious when exchanging money in the city center.
Many currency exchange spots offer poor rates, especially around tourist-heavy areas. We recommend heading to Panská Street, where you can compare several exchange offices before committing. Also, beware of “0% commission” signs—these are often just marketing tricks.
2. Stay close to the city center.
While staying outside the center might be budget-friendly in cities like Paris or Barcelona, this isn’t usually the case in Prague. Cheaper accommodations in remote areas often come with fewer amenities and limited access to restaurants and local spots. Staying central ensures better convenience, especially for business travelers.
3. Think twice before renting a car.
Prague is one of the most stressful cities in Europe to drive in, thanks to dense tram networks and narrow streets. Instead, use public transport or ride-sharing apps like Uber and Bolt—they're affordable and efficient.
4. Take advantage of lunch menus.
Save up to 30% by choosing the fixed-price lunch menus offered by most restaurants in Prague. This isn’t limited to Czech cuisine—even international and fast-food spots provide midday deals. It’s a great way to eat well on a budget while working or exploring between meetings.
5. Only have a few hours but still want to explore? Join our free walking tour to learn about Prague from fun guides!
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Author: Valeriia Zahradnikova and Vaclav Zahradnik, Prague guides certified by Prague City Tourism agency. Valeriia and Vaclav have worked in tourism for over 7 years and have guided thousands of Prague visitors.